Hi @alrei263,
Yes, it’s possible.
First, make sure you have spacedesk Driver on your mini-pc and is set to automatic start at system boot time (option is on spacedesk Driver Console -> Control). And since your client is Android phone you can connect via Android USB cable also make sure that “Android USB cable” is enabled (spacedesk Driver Console -> Communication Interfaces).
To setup your spacedesk display as main monitor:
1. While physical main monitor is still attached, connect with your Android phone via spacedesk Android USB cable connection.
2. Open display settings window on primary machine:
— set your spacedesk display as primary/main display
— if spacedesk display number shows “2”, there’s a dropdown menu where you can select “Show only on 2” and it will detach the main monitor display (probably display #1) OR switch to “second screen only” mode via display switch (Windows logo + P hotkey), then you can detach now your physical main monitor.