First of all: You can always uninstall spacedesk in Safe Mode. Just look at the instruction manual on https://manual.spacedesk.net There is a chapter “UNINSTALL ON WINDOWS PRIMARY MACHINE” and “Troubleshooting Uninstall”.
Second: Since you are talking about contemporary Windows (Windows 11 or 10), we can hardly imagine how the problem could be related to spacedesk. WDDM IddCx Display Drivers are not known to have such side effects (*). However, if you like we could still analyze details of your case. Then on Monday our team could instruct you how to create and send logfiles.
(*) Only in case of Legacy Windows (8.1 and 7) such a problem could theoretically be related to spacedesk. In rare cases, Legacy WDDM Hook Display Drivers might expose such side effects.