When I initially tried to get the Windows Spacedesk application/driver to connect to the Spacedesk app on my Android tablet over USB, it simply did not work. I got the popup on my tablet asking if I wanted to transfer files, photos, or just charge, and no matter what I picked or if I just hit the Cancel button, the connection never started. The System Information section on the Spacedesk Windows application showed an error with code 10. I found nothing useful in all the other diagnostic logs.
In order to make it work properly, I had to turn on Developer Options on the Android tablet and then I needed to enable USB debugging. Once I did that, it worked like a champ, but clearly a user should not have to jump through such hoops. The tablet is running Android 10.